GSK4418959 (enantiomer)
GSK4418959 enantiomer is the enantiomer of GSK4418959. GSK4418959 (IDE275) is a non-covalent, reversible, selective helicase inhibitor of WRN with oral bioavailability. It competitively inhibits ATPase and DNA unwinding functions in an ATP-dependent manner. GSK4418959 is utilized in the study of microsatellite instability-high (MSI-H) cancer.
Product Specifications
CAS Number
3064599-37-4
Field of Research
Cell Biology, Molecular Biology
Smiles
C (O) (=O) [C@H]1[C@@H] (CCC[C@@H]1C (NC2=C (F) C=C (C (F) (F) F) C=C2) =O) C3=CC=C (N (S (=O) (=O) C=4C=C5C (=CC4) N (C) C (C) =N5) C) C=C3
Molecular Formula
C31H30F4N4O5S
Molecular Weight
646.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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