(R, R) -VRT-534
(R, R) -VRT-534 is the (R, R) -enantiomer of VRT-534. VRT-534 (Compound 3) acts as a chemical chaperone targeting connexin 26 (Cx26) . VRT-534 demonstrates dose-dependent binding with recombinant WT Cx26 and mutant Cx26 K188N, with EC50 values of 19 μM and 5 μM, respectively. VRT-534 is applicable in research related to hearing impairments.
Product Specifications
CAS Number
926664-33-7
Field of Research
Signal Transduction
Smiles
C (NC=1SC ([C@@H] (C2=C (Cl) C=CC=C2) N3C[C@H] (O) CC3) =CN1) (=O) C4 (CC4) C=5C=C6C (=CC5) OCO6
Molecular Formula
C25H24ClN3O4S
Molecular Weight
497.99
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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