Pomalidomide-6-OH
Product Specifications
UNSPSC Description
Pomalidomide-6-OH is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-OH can be connected to the ligand for protein by a linker to form PROTAC[1].
Target Antigen
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-6-oh.html
Smiles
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(N)=CC(O)=C3)=O)=O
Molecular Weight
289.247
References & Citations
[1]Andrew J. Phillips, et al. Bromodomain targeting degronimers for target protein degradation. WO2017197056A1.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139540/Pomalidomide-6-OH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139540/Pomalidomide-6-OH-SDS-MedChemExpress.pdf
CAS Number
1547162-44-6
Available Sizes
Curated Selection
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