Noggin, Mouse (CHO)

Product Specifications

UNSPSC Description

Noggin Protein, Mouse (CHO) is a bone morphogenetic protein (BMP) antagonist.

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/noggin-protein-mouse-cho.html

Purity

97.00

Smiles

LRAAPAGGQH YLHIRPAPSD NLPLVDLIEH PDPIFDPKEK DLNETLLRSL LGGHYDPGFM ATSPPEDRPG GGGGPAGGAE DLAELDQLLR QRPSGAMPSE IKGLEFSEGL AQGKKQRLSK KLRRKLQMWL WSQTFCPVLY AWNDLGSRFW PRYVKVGSCF SKRSCSVPEG MVCKPSKSVH LTVLRWRCQR RGGQRCGWIP IQYPIISECK CSC

Molecular Weight

Approximately 28-31 kDa due to the glycosylation.

References & Citations

[1]Valenzuela DM, et al. Identification of mammalian noggin and its expression in the adult nervous system. J Neurosci. 1995 Sep;15(9):6077-84.|[2]Brunet LJ, et al. Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton. Science. 1998 May 29;280(5368):1455-7.|[3]Smith WC, et al. Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm. Nature. 1993 Feb 11;361(6412):547-9.|[4]Groppe J, et al. Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. Nature. 2002 Dec 12;420(6916):636-42.