Dichotomine C
Dichotomine C ((R) - (-) -Dichotomine C) is a β-carboline alkaloid with anti-allergic properties. It inhibits the release of β-hexosaminidase from RBL-2H3 cells with an IC50 of 62 μM. Additionally, it suppresses antigen IgE-mediated release of TNF-α and IL-4 in RBL-2H3 cells, with IC50 values of 19 μM and 15 μM, respectively. This compound is applicable in the research of type I hypersensitivity reactions.
Product Specifications
CAS Number
755036-45-4
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research
Smiles
[C@@H] (CO) (O) C1=C2C (C=3C (N2) =CC=CC3) =CC (C (OC) =O) =N1
Molecular Formula
C15H14N2O4
Molecular Weight
286.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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