Eteplirsen (sodium)
Eteplirsen (AVI 4658) sodium is a synthetic antisense oligonucleotide that induces dystrophin production. Eteplirsen (AVI 4658) sodium promotes exon 51 skipping in Duchenne muscular dystrophy patients and can be used in Duchenne muscular dystrophy research[1].
Product Specifications
Product Name Alternative
AVI 4658 (sodium)
UNSPSC
12352208
Target
Others
Type
Oligonucleotides
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/eteplirsen-sodium.html
Purity
91.16
Solubility
10 mM in H2O
Smiles
[Eteplirsen(sodium)]
Molecular Formula
C364H539N177Na30O122P30
Molecular Weight
10306 (free acid)
References & Citations
[1]Kenji Rowel Q Lim, et al. Eteplirsen in the treatment of Duchenne muscular dystrophy. Drug Des Devel Ther. 2017 Feb 28;11:533-545.|[2]Charleston J, et al. Long-term treatment with eteplirsen promotes exon 51 skipping and novel dystrophin protein production in duchenne muscular dystrophy patients[J]. Neuromuscular Disorders, 2016, 26: S153.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 3
Available Sizes
Curated Selection
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