Deoxythymidine-5'-triphosphate-13C10 (dilithium)

Deoxythymidine-5'-triphosphate-13C10 (dTTP-13C10) dilithium is 13C-labeled Deoxythymidine-5'-triphosphate (HY-138615) . Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.

Product Specifications

Product Name Alternative

DTTP-13C10 (dilithium)

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/deoxythymidine-5-triphosphate-13c10-dilithium.html

Concentration

100 mM in 99.2 μL Tris HCl/H2O buffer pH=7.5

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O=[13C](N1[13C@H]2[13CH2][13C@H](O)[13C@@H]([13CH2]OP(O)(OP(OP(O)(O[Li])=O)(O[Li])=O)=O)O2)N[13C]([13C]([13CH3])=[13CH]1)=O

Molecular Formula

13C10H15Li2N2O14P3

Molecular Weight

503.96

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975;5 (2) :191-202.