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(S, R, S) -AHPC-Ac

(S, R, S) -AHPC-Ac is a ligand for E3 ubiquitinase. (S, R, S) -AHPC-Ac can be used to synthesize PROTAC SMARCA2/4-degrader-22.

Product Specifications

CAS Number

2361116-63-2

UNSPSC

12352005

Target

Ligands for E3 Ligase

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-ac.html

Smiles

CC(C)(C)[C@H](N)C(N1[C@@H](C[C@H](C1)OC(C)=O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O

Molecular Formula

C24H32N4O4S

Molecular Weight

472.60

References & Citations

[1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. USA, US20230072658A1 2020-12-17

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Von Hippel-Lindau (VHL)

Frequently Asked Questions

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