Aminooxy-amido-PEG4-propargyl
Product Specifications
UNSPSC Description
Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aminooxy-amido-peg4-propargyl.html
Smiles
NOCC(NCCOCCOCCOCCOCC#C)=O
Molecular Weight
304.34
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-133435/Aminooxy-amido-PEG4-propargyl-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-133435/Aminooxy-amido-PEG4-propargyl-SDS-MedChemExpress.pdf
CAS Number
2253965-03-4
Available Sizes
Curated Selection
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