PDGFRα kinase-IN-2
PDGFRαkinase-IN-2 is a potent inhibitor of PDGFR-α with an IC50 of 2.1 nM. It exhibits anticancer activity against human colon cancer HT-29 cells, with an IC50 of 1.48 μM. Additionally, PDGFRαkinase-IN-2 demonstrates anti-angiogenic properties in zebrafish models with low embryotoxicity, making it suitable for research in colon cancer and anti-angiogenesis.
Product Specifications
CAS Number
3066103-58-7
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
O=C (NC1=CC=C (C=C1) NC=2N=CN=C3C=C (OC) C (OC) =CC32) NC4=CC=CC (=C4) C
Molecular Formula
C24H23N5O3
Molecular Weight
429.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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