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Antifolate agent 1

Antifolateagent 1 (Compound 1) is an antifolate agent featuring a single-carbon bridge. It lacks RFC transport, shows no affinity for FRα and FRβ, and exhibits no GARFTase inhibition activity. Antifolateagent 1 serves as a negative control in the development of folate receptor-targeted antifolate agents.

Product Specifications

CAS Number

518063-75-7

Field of Research

Cell Biology

Smiles

O=C1C2=C (NC (CC3=CC=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3) =C2) NC (N) =N1

Molecular Formula

C19H19N5O6

Molecular Weight

413.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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