Antifolate agent 1
Antifolateagent 1 (Compound 1) is an antifolate agent featuring a single-carbon bridge. It lacks RFC transport, shows no affinity for FRα and FRβ, and exhibits no GARFTase inhibition activity. Antifolateagent 1 serves as a negative control in the development of folate receptor-targeted antifolate agents.
Product Specifications
CAS Number
518063-75-7
Field of Research
Cell Biology
Smiles
O=C1C2=C (NC (CC3=CC=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3) =C2) NC (N) =N1
Molecular Formula
C19H19N5O6
Molecular Weight
413.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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