CCX354
CCX354 is an antagonist of CCR1, with anti-inflammatory activity.
Product Specifications
CAS Number
[1010073-75-2]
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/ccx354.html
Purity
99.18
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC(N2CCN(C(CN3N=C(C4=NC=CN4)C5=CC=CN=C53)=O)CC2)=CC=C1Cl
Molecular Formula
C22H22ClN7O2
Molecular Weight
451.91
References & Citations
[1]Compounds for the treatment of osteoporosis and cancers. US 20100113472 A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
CCR1
Available Sizes
Curated Selection
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