K-833
K-833 is a GPR119 agonist with EC50 values of 39.8 nM, 100 nM, 75.4 nM, and 12.6 nM for human, mouse, rat, and dog respectively. In acute intestinal peptide secretion in mice, K-833 modestly increases the secretion of glucagon-like peptide-1 (GLP-1) and, when used in combination with AM-5262, can synergistically enhance GLP-1 levels. K-833 is applicable in weight loss research.
Product Specifications
CAS Number
2639936-77-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (CC1=C (F) C=C (OCCCC2CCN (CC2) C=3N=CC (Cl) =CN3) C=C1) (=O) N4CC (CNC[C@@H] ([C@H] ([C@@H] ([C@@H] (CO) O) O) O) O) C4
Molecular Formula
C30H43ClFN5O7
Molecular Weight
640.14
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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