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URAT1-IN-14

URAT1-IN-14 is a potent and orally active inhibitor of uric acid transporter 1 (URAT1) . It demonstrates an IC50 value of 0.72 μM for inhibiting human URAT1 in HEK293 cells and exhibits low cytotoxicity in Hep-G2 cells. URAT1-IN-14 reduces uric acid levels in a hyperuricemia mouse model and is applicable in research on hyperuricemia and gout.

Product Specifications

CAS Number

2516232-89-4

Field of Research

Pharmacology & Drug Discovery

Smiles

O=C (O) C1 (SC=2C=CC=CC2N3C=4C=CC=CC4OCC3) CCC1

Molecular Formula

C19H19NO3S

Molecular Weight

341.42

Storage Conditions

-20°C

Notes

For research use only.

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