FLT3-IN-19
Product Specifications
UNSPSC Description
FLT3-IN-19 (Comp 50) is a potent and selective FLT3 inhibitor with IC50 of 0.213 nM. FLT3-IN-19 can be used in AML disease research[1].
Target Antigen
FLT3
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flt3-in-19.html
Solubility
DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C1=NNC=C1NC2=NC(C)=NC3=C2CCC3)NC4=CC=C(N5CCNCC5)C=C4
Molecular Weight
418.49
References & Citations
[1]Yanle Zhi, et al. Discovery of the selective and efficacious inhibitors of FLT3 mutations. Eur J Med Chem. 2018 Jul 15;155:303-315.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153473/FLT3-IN-19-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153473/FLT3-IN-19-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2237234-48-7
Available Sizes
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