Versipelostatin

Versipelostatin is a GRP78/Bip molecular chaperone down-regulator and can be isolated from the culture broth of Streptomyces versipellis 4083-SVS6[1].

Product Specifications

CAS Number

[477201-98-2]

UNSPSC

12352005

Target

HSP

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/versipelostatin.html

Solubility

10 mM in DMSO

Smiles

CC[C@]12[C@@]3([H])[C@]([C@H](CC([C@@H]3C)=O)O)([H])C=C([C@@]1([H])/C(CC)=C/[C@@H](C[C@H]([C@@H]([C@@H](CCC[C@]4([C@@]5(C[C@H](C(C)=C4)C)C(O)=C(C(O5)=O)C2=O)C)C)O[C@H]6C[C@@H]([C@@H]([C@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O[C@H]8C[C@@H]([C@@H]([C@H](O8)C)O)O)OC)O)C)CO)C

Molecular Formula

C61H94O17

Molecular Weight

1099.39

References & Citations

[1]Hae-Ryong Park, et al. Versipelostatin, a novel GRP78/Bip molecular chaperone down-regulator of microbial origin. Tetrahedron Letters 43 (2002) 6941–6945.