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NLRP3-IN-82

NLRP3-IN-82 (Compound 2b) is an NLRP3 inhibitor that significantly suppresses IL-1β release in HMDM cells with an IC50 of less than 5 nM. This compound is applicable for research into neurological disorders such as Alzheimer's disease, inflammatory conditions like inflammatory bowel disease, and metabolic disorders such as obesity.

Product Specifications

CAS Number

3091347-92-8

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

CN1C[C@]2 (N (C=3C=4N (C (=NN3) C5=C (O) C=C (Cl) C (C) =C5) C=CN4) CC[C@]2 (CC1) [H]) [H]

Molecular Formula

C20H23ClN6O

Molecular Weight

398.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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