NLRP3-IN-82
NLRP3-IN-82 (Compound 2b) is an NLRP3 inhibitor that significantly suppresses IL-1β release in HMDM cells with an IC50 of less than 5 nM. This compound is applicable for research into neurological disorders such as Alzheimer's disease, inflammatory conditions like inflammatory bowel disease, and metabolic disorders such as obesity.
Product Specifications
CAS Number
3091347-92-8
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
CN1C[C@]2 (N (C=3C=4N (C (=NN3) C5=C (O) C=C (Cl) C (C) =C5) C=CN4) CC[C@]2 (CC1) [H]) [H]
Molecular Formula
C20H23ClN6O
Molecular Weight
398.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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