PROTAC BET Degrader-13
PROTACBET Degrader-13 (Compound 34) is a TRIM21-based PROTAC (TRIMTAC) degrader that targets BET proteins. It effectively degrades the PML-eGFP-BRD4 fusion protein, causing a near-complete loss of EGFP+ nuclear foci with an EC50 of 1.4 μM.
Product Specifications
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.
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