TD034
TD034 is a selective, reversible, non-covalent inhibitor of HDAC11, with an IC50 of 5.1 nM and a Ki of 1.5 nM. It does not inhibit other HDACs or sirtuins. TD034 inhibits the desuccinylation of SHMT2 (a substrate of HDAC11) and lowers YAP1 levels by inhibiting HDAC11. TD034 is applicable for lung cancer research.
Product Specifications
CAS Number
3030718-42-1
Field of Research
Epigenetics & Chromatin, Molecular Biology, Stem Cell & Developmental Biology
Smiles
C (CCCCCCCCCC) [C@@H]1[C@@H] (C (CCCCC[C@@H]2NC (=O) [C@@]3 (N (C (=O) [C@H] (CC4=CC=CC=C4) NC (=O) [C@H] (CC5=CC=CC=C5) NC2=O) CCCC3) [H]) =O) O1
Molecular Formula
C45H64N4O6
Molecular Weight
757.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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