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AXT-914

AXT-914 is an inhibitor of the calcium-sensing receptor (CaSR) . It exhibits antiviral activity against coronaviruses HCoV 229E and SARS-CoV2. AXT-914 reduces cytoplasmic calcium signaling activity caused by CaSR mutations. It is applicable in research on Bartter syndrome type 5, autosomal dominant hypocalcemia (ADH), and coronavirus infections.

Product Specifications

CAS Number

717104-43-3

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Smiles

O=C1N=C (C=2C=CC (=CC2) C (C) C) C=3C=C (OCC#C) C=CC3N1CC4=CC=C (Br) C=C4

Molecular Formula

C27H23BrN2O2

Molecular Weight

487.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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