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N-Didesmethyladitoprim

N-Didesmethyladitoprim is a metabolite of Aditoprim, which acts as a selective inhibitor of bacterial dihydrofolate reductase (DHFR) . Aditoprim exhibits inhibitory concentration (IC50) values of 47 nM for Escherichia coli and 520 nM for Lactobacillus casei DHFR. It impedes the reduction of dihydrofolate to tetrahydrofolate. Aditoprim demonstrates broad-spectrum antibacterial activity and excellent pharmacokinetics.

Product Specifications

CAS Number

56066-19-4

Field of Research

Cell Biology, Infectious Disease & Virology, Metabolism Research

Smiles

N=1C=C (C (=NC1N) N) CC2=CC (OC) =C (N) C (OC) =C2

Molecular Formula

C13H17N5O2

Molecular Weight

275.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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