N-Didesmethyladitoprim
N-Didesmethyladitoprim is a metabolite of Aditoprim, which acts as a selective inhibitor of bacterial dihydrofolate reductase (DHFR) . Aditoprim exhibits inhibitory concentration (IC50) values of 47 nM for Escherichia coli and 520 nM for Lactobacillus casei DHFR. It impedes the reduction of dihydrofolate to tetrahydrofolate. Aditoprim demonstrates broad-spectrum antibacterial activity and excellent pharmacokinetics.
Product Specifications
CAS Number
56066-19-4
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research
Smiles
N=1C=C (C (=NC1N) N) CC2=CC (OC) =C (N) C (OC) =C2
Molecular Formula
C13H17N5O2
Molecular Weight
275.31
Storage Conditions
-20°C
Notes
For research use only.
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