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6PGD-IN-2

6PGD-IN-2 is a non-competitive inhibitor of 6-phosphogluconate dehydrogenase (6PGD) with an IC50 value of 5.1 μM. It disrupts 6PGD oligomerization in a substrate-dependent manner and induces the production of NADPH and Ru-5-P while reducing DNA synthesis in A549 cells. 6PGD-IN-2 is applicable in research on non-small cell cancer and liver cancer.

Product Specifications

Field of Research

Cell Biology, Metabolism Research, Molecular Biology

Storage Conditions

-20°C

Notes

For research use only.

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