Avermectin B1a
Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
Product Specifications
CAS Number
65195-55-3
Product Name Alternative
Abamectin B1a
UNSPSC
12352005
Hazard Statement
H300+H330, H372, H410
Target
Antibiotic; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Avermectin-B1a.html
Purity
98.26
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@H](CC)[C@]1([H])[C@@H](C)C=C[C@@]2(O[C@@]3([H])C[C@]([H])(OC([C@@]4([H])[C@@](/C(CO5)=C/C=C/[C@H](C)[C@H](O[C@@]6([H])C[C@H](OC)[C@@H](O[C@]7([H])O[C@@H](C)[C@H](O)[C@@H](OC)C7)[C@H](C)O6)/C(C)=C/C3)(O)[C@@]5([H])[C@H](O)C(C)=C4)=O)C2)O1
Molecular Formula
C48H72O14
Molecular Weight
873.08
Precautions
H300+H330, H372, H410
References & Citations
[1]Sun Y, et al. [Effects of avermectin B1a on soil microorganism and earthworm (Eisenia fetida) ]. Ying Yong Sheng Tai Xue Bao. 2005 Nov;16 (11) :2140-3.|[2]Sun Y, et al. Bioaccumulation and elimination of avermectin B1a in the earthworms (Eisenia fetida) . Chemosphere. 2005 Jul;60 (5) :699-704|[3]Huang J, et al. Avermectin B1a binds to high- and low-affinity sites with dual effects on the gamma-aminobutyric acid-gated chloride channel of cultured cerebellar granule neurons. J Pharmacol Exp Ther. 1997 Apr;281 (1) :261-6.|[4]Payne GT, et al. Activation of gamma-aminobutyric acid insensitive chloride channels in mouse brain synaptic vesicles by avermectin B1a.
 J Biochem Toxicol. 1991 Winter;6 (4) :283-92.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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