RORγ inverse agonist 2
RORγinverse agonist 2 (Compound 15) is a potent inverse agonist of the retinoic acid receptor-related orphan receptor RORγ, with IC50 values of 0.4 μM for Gal4-RORγ and 0.9 μM for full-length RORγ. This compound is useful for researching autoimmune diseases.
Product Specifications
CAS Number
1242610-59-8
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (O) (=O) [C@]12[C@@] ([C@@]3 ([C@@] (C) (CC1) [C@@]4 (C) [C@] (CC3) ([C@]5 (C) [C@@] (CC4) (C (C) (C) C (=O) /C (=C\C6=CC=CO6) /C5) [H]) [H]) [H]) ([C@H] (C (C) =C) CC2) [H]
Molecular Formula
C35H48O4
Molecular Weight
532.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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