TL033 TFA
TL033 TFA is a component of an antibody-drug conjugate (drug-linker conjugate for ADC) . It comprises a linker and a bioactive small molecule toxin. TL033 TFA can be conjugated with the antibody Sacituzumab (anti-Trop-2) to synthesize BT001021, which exhibits anticancer activity against various cancers, including breast cancer, non-small cell lung cancer (NSCLC), and gastric cancer.
Product Specifications
CAS Number
2746343-70-2
Field of Research
Immunology & Inflammation
Smiles
C (C (O) =O) (F) (F) F.O=C1N2C (C=3C (C2) =C (CCN (S (C) (=O) =O) C (C) C) C=4C (N3) =CC=CC4) =CC5=C1COC (=O) [C@]5 (OC (OCC6=CC=C (NC ([C@@H] (NC (COCC (NCCOCCOCCOCCOCCOCCOCCOCCOCCN7C=C (CNC (CCCC#CC=8C=NC (S (C) (=O) =O) =NC8) =O) N=N7) =O) =O) CCCCN) =O) C=C6) =O) CC
Molecular Formula
C78H104F3N13O25S2
Molecular Weight
1744.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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