HDAC1/6-IN-3
HDAC1/6-IN-3 is an effective HDAC inhibitor with significant inhibitory effects on HDAC1 (IC50= 1.1 nM) and HDAC6 (IC50= 2.7 nM) . In HepG2 cells, it causes cell cycle arrest at the G0/G1 phase and induces apoptosis and pyroptosis. Furthermore, HDAC1/6-IN-3 demonstrates notable antitumor activity in HepG2 tumor xenograft models. This compound is applicable for cancer research, including studies on liver, lung, colon, and breast cancers.
Product Specifications
CAS Number
3038691-85-6
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology
Smiles
O=C (NO) CCCCCC (=O) N (C1=CC=C (OC) C=C1) CC=2N=C (SC2) C=3C=CC=CC3
Molecular Formula
C24H27N3O4S
Molecular Weight
453.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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