Rel-A-395 hydrochloride
Rel-A-395 hydrochloride is the relative configuration of A-395 hydrochloride. A-395 is an antagonist of protein-protein interactions within the polycomb repressive complex 2 (PRC2) . It inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 value of 18 nM.
Product Specifications
CAS Number
2747996-65-0
Field of Research
Cancer Biology, Epigenetics & Chromatin
Smiles
FC1=C2C (CCC2=CC=C1) N3C[C@@H] ([C@@H] (N (C) C) C3) C4=CC=C (C=C4) N5CCN (S (C) (=O) =O) CC5.Cl
Molecular Formula
C26H36ClFN4O2S
Molecular Weight
523.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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