Faridoxorubicin
Faridoxorubicin (AVA-6000) is a prodrug that targets fibroblast activation protein alpha (FAPα) . It releases active doxorubicin through FAPα-mediated cleavage, enhancing drug exposure within tumors while reducing cardiac toxicity. Faridoxorubicin holds potential for research in solid tumors, such as liver metastases from colorectal cancer.
Product Specifications
CAS Number
1841402-73-0
Smiles
OC=1C2=C ([C@@H] (O[C@H]3C[C@H] (NC (=O) [C@H]4N (C ([C@H] (NC (=O) C=5C=CN=CC5) C) =O) CCC4) [C@H] (O) [C@H] (C) O3) C[C@@] (C (CO) =O) (O) C2) C (O) =C6C1C (=O) C=7C (C6=O) =C (OC) C=CC7
Molecular Formula
C41H44N4O14
Molecular Weight
816.81
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HK200807 1 Kit
Apolipoprotein CII (APOC2) Human qPCR Template Standard (NM_000483)
Sign In for Pricing
View Details ![2-[4- (tert-Butyl) phenyl]-5- (2-chloro-5-nitrophenyl) -1,3,4-oxadiazole](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
OR21617 100 mg
2-[4- (tert-Butyl) phenyl]-5- (2-chloro-5-nitrophenyl) -1,3,4-oxadiazole
Sign In for Pricing
View Details 
MBS8113941-01 0.3 mg
Human Aminoacylase 1 Baculovirus-Insect cells Overexpression Lysate
Sign In for Pricing
View Details MBS8113941-02 5x 0.3 mg
Human Aminoacylase 1 Baculovirus-Insect cells Overexpression Lysate
Sign In for Pricing
View Details