Theophylline-platinum (IV) prodrug-1
Theophylline-platinum (IV) prodrug-1 is a PARP-1 inhibitor. It enhances DNA damage, ROS generation, mitochondrial dysfunction, apoptosis, and S-phase arrest in SKOV3-BRCA1-KD cells while reducing invasion and metastasis. Additionally, it exhibits strong antitumor activity in SKOV3-BRCA1-KD xenograft tumor models. This compound is used for ovarian cancer research.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Storage Conditions
-20°C
Notes
For research use only.
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