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Nrf2-IN-4

Nrf2-IN-4 is an Nrf2 inhibitor that induces ferroptosis by disrupting cellular iron homeostasis, promoting ferritin degradation, and ultimately triggering ferroptosis. It activates lysosomes through iron-dependent reactive oxygen species (ROS) production and lysosomal acidification. Nrf2-IN-4 demonstrates significant antitumor effects and is applicable in breast cancer research.

Product Specifications

CAS Number

2417486-06-5

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

ClC=1C=CC (=CC1Cl) C=2N=C (SC2) NN=C (C3=NC=CC=C3) C4=NC=CC=C4

Molecular Formula

C20H13Cl2N5S

Molecular Weight

426.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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