Nrf2-IN-4
Nrf2-IN-4 is an Nrf2 inhibitor that induces ferroptosis by disrupting cellular iron homeostasis, promoting ferritin degradation, and ultimately triggering ferroptosis. It activates lysosomes through iron-dependent reactive oxygen species (ROS) production and lysosomal acidification. Nrf2-IN-4 demonstrates significant antitumor effects and is applicable in breast cancer research.
Product Specifications
CAS Number
2417486-06-5
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
ClC=1C=CC (=CC1Cl) C=2N=C (SC2) NN=C (C3=NC=CC=C3) C4=NC=CC=C4
Molecular Formula
C20H13Cl2N5S
Molecular Weight
426.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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