LGT-1

LGT-1 is a PD-L1 ligand. The compound labeled with 18F shows exceptional specificity and uptake in B16-F10 tumor cells and demonstrates high tumor uptake with relatively low liver uptake in mouse models carrying B16-F10 tumors, while maintaining good stability. LGT-1 can be utilized as a radiotracer for PET imaging of tumor PD-L1 expression.