MRT-23227
MRT-23227 is a molecular glue degrader targeting cereblon (CRBN) . It forms a ternary complex with CRBN and G3BP2, which activates the ubiquitin-proteasome system to degrade G3BP2. MRT-23227 shows potential for research in G3BP2-related cancers (such as breast cancer and lung cancer) and neurodegenerative diseases.
Product Specifications
CAS Number
3050683-03-6
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (C=2C=CC=C (C=3C=CC (OCC4=NN (C=C4) C) =CC3) C2Cl) CC1
Molecular Formula
C22H20ClN3O3
Molecular Weight
409.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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