MAPK-IN-5
MAPK-IN-5 is a potent inhibitor of MAPK, with an IC50 value of 1.35 μM in HeLa cells. It induces ROS-mediated DNA damage and mitochondrial apoptosis (apoptosis) via the MAPK pathway. MAPK-IN-5 significantly inhibits colony formation in HeLa cells, reduces viable cell numbers, suppresses cell migration, and arrests the cell cycle at the G2/M phase. It is applicable in cervical cancer research.
Product Specifications
CAS Number
2579683-39-7
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Protein Biochemistry, Signal Transduction
Smiles
FC (F) (F) C1=CC=C (C=C1) CN2N=NC (=C2) C=3C=CC=C (C3) NC=4N=CN=C5C=C (OCCOC) C (OCCOC) =CC54
Molecular Formula
C30H29F3N6O4
Molecular Weight
594.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PROTP05109-1 20 µg
S100A8 S100 Calcium Binding Protein A8 Human Recombinant Protein
Sign In for Pricing
View Details 
26318151 3x 1.0 µg DNA
LASP1 CRISPR All-in-one AAV vector set (with saCas9)(Human)
Sign In for Pricing
View Details 24038121 3x 1.0µg DNA
HSPD1P17 CRISPRa sgRNA lentivector (set of three targets)(Human)
Sign In for Pricing
View Details 