MAPK-IN-5
MAPK-IN-5 is a potent inhibitor of MAPK, with an IC50 value of 1.35 μM in HeLa cells. It induces ROS-mediated DNA damage and mitochondrial apoptosis (apoptosis) via the MAPK pathway. MAPK-IN-5 significantly inhibits colony formation in HeLa cells, reduces viable cell numbers, suppresses cell migration, and arrests the cell cycle at the G2/M phase. It is applicable in cervical cancer research.
Product Specifications
CAS Number
2579683-39-7
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Protein Biochemistry, Signal Transduction
Smiles
FC (F) (F) C1=CC=C (C=C1) CN2N=NC (=C2) C=3C=CC=C (C3) NC=4N=CN=C5C=C (OCCOC) C (OCCOC) =CC54
Molecular Formula
C30H29F3N6O4
Molecular Weight
594.58
Storage Conditions
-20°C
Notes
For research use only.
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