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N'-Isonicotinoylisonicotinohydrazide

N'-Isonicotinoylisonicotinohydrazide (Compound 7, 1,2-Diisonicotinoylhydrazine) is a competitive inhibitor of bacterial heme oxygenase (HO) with an IC50 ranging from 5 to 30 μM. It impedes the release and uptake of iron in bacteria and shows selective activity against HO enzymes from Pseudomonas aeruginosa and Neisseria meningitidis. This compound holds potential for research in treating infections caused by multidrug-resistant Gram-negative bacteria.

Product Specifications

CAS Number

4329-75-3

Field of Research

Immunology & Inflammation, Infectious Disease & Virology

Smiles

O=C (NNC (=O) C=1C=CN=CC1) C=2C=CN=CC2

Molecular Formula

C12H10N4O2

Molecular Weight

242.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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