N'-Isonicotinoylisonicotinohydrazide
N'-Isonicotinoylisonicotinohydrazide (Compound 7, 1,2-Diisonicotinoylhydrazine) is a competitive inhibitor of bacterial heme oxygenase (HO) with an IC50 ranging from 5 to 30 μM. It impedes the release and uptake of iron in bacteria and shows selective activity against HO enzymes from Pseudomonas aeruginosa and Neisseria meningitidis. This compound holds potential for research in treating infections caused by multidrug-resistant Gram-negative bacteria.
Product Specifications
CAS Number
4329-75-3
Field of Research
Immunology & Inflammation, Infectious Disease & Virology
Smiles
O=C (NNC (=O) C=1C=CN=CC1) C=2C=CN=CC2
Molecular Formula
C12H10N4O2
Molecular Weight
242.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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