FHND5032
FHND5032 is an orally active miR-124 inducer that significantly enhances miR-124 expression in macrophages. It inhibits the PIK3R2/PI3K/Akt axis to block inflammatory signaling, facilitates macrophage reprogramming, and restores epithelial barrier function. FHND5032 alleviates colitis and reduces inflammatory burden in ulcerative colitis mouse models, making it useful for ulcerative colitis research.
Product Specifications
CAS Number
3076057-63-8
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction
Smiles
FC (F) (F) OC1=CC=C (C=C1) NC=2N=CC3=CC=C (Cl) C=C3N2
Molecular Formula
C15H9ClF3N3O
Molecular Weight
339.70
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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