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PFI-7-O-C4-piperazin

PFI-7-O-C4-piperazin is an E3 ligase ligand-linker conjugate used in the synthesis of PROTACs, such as NEP162. The E3 ligase ligand of NEP162 (PFI-7) is a highly selective GID4 antagonist (KD= 0.22 μM) . NEP162 is a potent and highly selective BRD4 PROTAC degrader with antitumor activity.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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