Odafosfamide
Odafosfamide ((S) -OBI-3424) is a highly selective prodrug bis-alkylating agent that is specifically activated by aldehyde-keto reductase 1C3 (AKR1C3), resulting in pronounced cytotoxicity toward tumor cell lines with elevated AKR1C3 expression, and it demonstrates significant antitumor activity in cancers such as liver cancer, non-small cell lung cancer, and leukemia, making it a targeted and mechanistically informative compound for precision oncology research.
Product Specifications
CAS Number
2097713-69-2
Field of Research
Metabolism Research
Smiles
C[C@@H] (C1=CC (OC2=CC (C (N (C) C) =O) =CC=C2) =C (C=C1) [N+] ([O-]) =O) OP (N3CC3) (N4CC4) =O
Molecular Formula
C21H25N4O6P
Molecular Weight
460.42
Storage Conditions
-20°C
Notes
For research use only.
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