Yoda2
Yoda2 (KC289), the potassium salt of Yoda1, is an agonist of PIEZO1 with an EC50 of 150 nM. It induces Ca2+ elevation in HeLa cells and can cause concentration-dependent and NO-dependent relaxation in mouse portal vein (EC50= 1.2 μM) . Additionally, Yoda2 is capable of stimulating NOS3 and promoting NO production.
Product Specifications
CAS Number
3081450-95-2
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
O=C (C1=CC=C (C2=NN=C (SCC3=C (Cl) C=CC=C3Cl) S2) C=C1) [O-].[K+]
Molecular Formula
C16H9Cl2KN2O2S2
Molecular Weight
435.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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