Yoda2
Yoda2 (KC289), the potassium salt of Yoda1, is an agonist of PIEZO1 with an EC50 of 150 nM. It induces Ca2+ elevation in HeLa cells and can cause concentration-dependent and NO-dependent relaxation in mouse portal vein (EC50= 1.2 μM) . Additionally, Yoda2 is capable of stimulating NOS3 and promoting NO production.
Product Specifications
CAS Number
3081450-95-2
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
O=C (C1=CC=C (C2=NN=C (SCC3=C (Cl) C=CC=C3Cl) S2) C=C1) [O-].[K+]
Molecular Formula
C16H9Cl2KN2O2S2
Molecular Weight
435.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
027428 96 Tests
Phospholipase A2, Group IIA (PLA2G2A) BioAssayTM ELISA Kit (Human)
Sign In for Pricing
View Details 
LV726408 1.0 µg DNA
FXYD6P2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details