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IDO1/TDO-IN-9

IDO1/TDO-IN-9 (Compound 66) is a potent dual inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO), with an IC50 value of less than 1 μM. It effectively inhibits the activity of IDO1 and TDO, preventing the degradation of tryptophan into kynurenine, thereby restoring immune activity in the tumor microenvironment and inhibiting tumor growth. IDO1/TDO-IN-9 shows potential for cancer research.

Product Specifications

CAS Number

1878200-88-4

Field of Research

Metabolism Research

Smiles

FC1=CC2=C (N=C1Cl) ON=C2N

Molecular Formula

C6H3ClFN3O

Molecular Weight

187.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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