IDO1/TDO-IN-9
IDO1/TDO-IN-9 (Compound 66) is a potent dual inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO), with an IC50 value of less than 1 μM. It effectively inhibits the activity of IDO1 and TDO, preventing the degradation of tryptophan into kynurenine, thereby restoring immune activity in the tumor microenvironment and inhibiting tumor growth. IDO1/TDO-IN-9 shows potential for cancer research.
Product Specifications
CAS Number
1878200-88-4
Field of Research
Metabolism Research
Smiles
FC1=CC2=C (N=C1Cl) ON=C2N
Molecular Formula
C6H3ClFN3O
Molecular Weight
187.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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