SEH-IN-21
SEH-IN-21 is an orally active inhibitor of sEH, exhibiting IC50 values of 0.1 nM for both hsEH and msEH. It significantly suppresses the NF-κB signaling pathway. sEH-IN-21 demonstrates potent anti-inflammatory activity by reducing IL-6 and TNF-α release and maintaining intestinal barrier integrity. It is applicable in research on inflammatory bowel disease (IBD) .
Product Specifications
CAS Number
3084814-46-7
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Smiles
N (C (N[C@H]1CC[C@H] (NC2=C (NS (=O) (=O) C3=CC=C (C) C=C3) C (=O) C2=O) CC1) =O) C45CC6 (C) CC (C) (C4) CC (C5) C6
Molecular Formula
C30H40N4O5S
Molecular Weight
568.73
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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