MrgprX2-IN-1
MrgprX2-IN-1 (Compound 2-10) is a selective antagonist of the Mas-related G protein-coupled receptor X2 (MRGPRX2) . It functions by inhibiting mast cell degranulation and the release of inflammatory mediators mediated by MRGPRX2, thereby blocking non-IgE-dependent immune responses. MrgprX2-IN-1 holds potential for research into pseudo-allergic reactions, chronic pruritus, and inflammatory diseases.
Product Specifications
CAS Number
2792202-91-4
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
N (C=1N2C (=NC (C (F) (F) F) =C2) C=CC1) [C@@H]3CC[C@H] (NC (=O) C4=C5C (C=NN5) =CC=C4) CC3
Molecular Formula
C22H21F3N6O
Molecular Weight
442.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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