ALG-097558
ALG-097558 is an orally active 3CL protease inhibitor. It demonstrates broad antiviral activity against various SARS-CoV-2 variants and other human coronaviruses, including SARS-CoV-1, α-HCoV 229E, and β-HCoV OC43. ALG-097558 exhibits potent inhibitory effects, with an IC50 of 2 nM for SARS-CoV-2 3CL protease and 6 nM for 229E 3CL protease. In a SARS-CoV-2 hamster infection model, ALG-097558 shows antiviral activity and can be used for research on viral infections.
Product Specifications
CAS Number
2892287-29-3
Field of Research
Infectious Disease & Virology
Smiles
C (N[C@@H] (C[C@H]1C (=O) NCC1) C#N) (=O) [C@@H]2[C@@]3 ([C@@] ([C@]4 (C[C@@]3 (C=C4) [H]) [H]) (CN2C ([C@@H] (NC (C (Cl) (F) F) =O) [C@] (C) (C) C) =O) [H]) [H]
Molecular Formula
C25H32ClF2N5O4
Molecular Weight
540.00
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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