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(±) -Desisopropylpropranolol

(±) -Desisopropylpropranolol (N-Desisopropylpropranolol) is a metabolite of Propranolol. Propranolol acts as a non-selective β-adrenergic receptor (βAR) antagonist with high affinity for both β1AR and β2AR, having Ki values of 1.8 nM and 0.8 nM, respectively. It inhibits the binding of [3H]-DHA to rat brain membrane preparations with an IC50 of 12 nM. Propranolol is used in studies related to hypertension, pheochromocytoma, myocardial infarction, arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.

Product Specifications

CAS Number

20862-11-7

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Smiles

OC (COC1=CC=CC=2C=CC=CC12) CN

Molecular Formula

C13H15NO2

Molecular Weight

217.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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