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LO-3-63

LO-3-63 is a Ribociclib analogue featuring a truncated fumaramide group and acts as a CDK4/6 degrader with PROTAC properties. It degrades CDK4/6 in cells via a CUL4DCAF16-dependent pathway.

Product Specifications

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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